R.J. REYNOLDS TOBACCO COMPANYDownload PDFPatent Trials and Appeals BoardMay 13, 202014878561 - (D) (P.T.A.B. May. 13, 2020) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/878,561 10/08/2015 Anthony Richard Gerardi R60999 10280US.D1 (1116.4 4795 26158 7590 05/13/2020 WOMBLE BOND DICKINSON (US) LLP ATTN: IP DOCKETING P.O. BOX 7037 ATLANTA, GA 30357-0037 EXAMINER HOLLAND, PAUL J ART UNIT PAPER NUMBER 1656 NOTIFICATION DATE DELIVERY MODE 05/13/2020 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): BostonPatents@wbd-us.com IPDocketing@wbd-us.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE ____________ BEFORE THE PATENT TRIAL AND APPEAL BOARD ____________ Ex parte ANTHONY RICHARD GERARDI, CRYSTAL DAWN HEGE BYRD, THADDEUS JUDE JACKSON, CHELSEA ALLISON COOKE, JOHN-PAUL MUA, and KYLE FORD 1 ____________ Appeal 2019-004466 Application 14/878,561 Technology Center 1600 ____________ Before JEFFREY N. FREDMAN, DEBORAH KATZ, and JOHN G. NEW, Administrative Patent Judges. NEW, Administrative Patent Judge. DECISION ON APPEAL 1 We use the word “Appellant” to refer to “applicant” as defined in 37 C.F.R. § 1.42. Appellant identifies R.J. Reynolds Tobacco Company as the real party-in-interest. App. Br. 1. Appeal 2019-004466 Application 14/878,561 2 SUMMARY Appellant files this appeal under 35 U.S.C. § 134(a) from the Examiner’s Final Rejection of claims 40, 53–59, and 62–66 as unpatentable under 35 U.S.C. § 103 over the combination of Zimmerman (US 2008/0178894 A1, July 31, 2008) (“Zimmerman”) as evidenced by Garger et al. (US 6,033,895, March 7, 2000) (“Garger”), and Curello et al. (US 2007/0077480 A1, April 5, 2007) (“Curello”). We have jurisdiction under 35 U.S.C. § 6(b). We AFFIRM, but designate our affirmance as a new ground of rejection. NATURE OF THE CLAIMED INVENTION Appellant’s claimed invention is directed to methods of purifying protein-enriched plant extracts. Abstract. The methods include removing metals from the plant extracts using commercially available functionalized resins. Spec. 15, ll. 1–21. REPRESENTATIVE CLAIM Claim 40 is representative of the claims on appeal and recites: 40. A method for modifying the content of a plant-derived, protein-enriched material, the method comprising receiving a plant-derived, protein-enriched material comprising RuBisCO, F2 fraction proteins, or a combination thereof, wherein the plant-derived, protein-enriched material further comprises one or more heavy metals; Appeal 2019-004466 Application 14/878,561 3 dissolving at least a portion of the plant-derived, protein- enriched material in a solvent to form a solution, contacting the plant-derived, protein-enriched material solution with a functionalized resin to afford a treated solution comprising a protein concentrate or isolate having a reduced amount of one or more of copper, cadmium, lead, and nickel as compared with the plant-derived, protein-enriched material, wherein the functionalized resin comprises a resin functionalized with a chelating group selected from the group consisting of triaminetetraacetic acid groups, salts thereof, and combinations thereof; and separating the treated solution from the functionalized resin. App. Br. 12. ISSUES AND ANALYSIS We agree with, and expressly adopt, the Examiner’s findings, reasoning, and conclusion that the claims are obvious over the combined cited prior art. We address below the arguments raised by Appellant. Issue 1 Appellant argues that the Examiner erred in combining Zimmerman and Curello because Curello is non-analogous art. App. Br. 4. Analysis The Examiner finds that Zimmerman teaches methods of selectively removing specific constituents from tobacco plant extracts. Final Act. 5 Appeal 2019-004466 Application 14/878,561 4 (citing Zimmerman Abstract). The Examiner finds that Zimmerman teaches forming an aqueous plant extract by contacting chopped tobacco plants with an aqueous solvent. Id. (citing Zimmerman ¶¶ 4–10; 28–41). The Examiner finds that Garger teaches that Zimmerman’s aqueous plant extract contains soluble proteins in two fractions: Fraction 1 (“F1”) which is “predominantly a photosynthetic protein, ribulose 1,5-diphosphate carboxylase (or RuBisCO), whose subunit molecular weight is about 550 kD,” and Fraction 2 (“F2”) which “contains a mixture of proteins and peptides whose subunit molecular weights typically range from about 3 kD to 100 kD.” Id. (citing Garger, col. 2, ll. 48–64). The Examiner finds that Zimmerman teaches contacting the aqueous plant extract with a functionalized resin to remove metals, including cadmium, lead, and nickel. Id. (citing Zimmerman ¶¶ 4, 36). The Examiner finds that Zimmerman teaches the functionalized resins may include “a chelating resin, such as iminodiacetate.” Id. (citing Zimmerman ¶ 4). The Examiner acknowledges that Zimmerman does not teach “a resin functionalized with a chelating group selected from the group consisting of triaminetetraacetic acid groups, salts thereof, and combinations thereof.” Final Act. 7. The Examiner finds that Curello teaches removing transition metal ions from fuel using “functionalized silica containing compounds commercially available from Silicycle, such as Si-Triaminetetracetic acid that removes metals such as palladium, nickel, and copper.” Id. (citing Curello Abstract, ¶ 49 (Table 1)). Examiner finds that “[Curello] is reasonably pertinent to the particular problem with which the appellant is concerned because Curello identifies functionalized resins that are commercially available for the removal of Appeal 2019-004466 Application 14/878,561 5 metal compounds from solutions through chelation.” Ans. 8 (citing In re Oetiker, 977 F.2d 1443 (Fed. Cir. 1992)). The Examiner finds that Curello’s functionalized silica resins are analogous to Zimmerman’s functional resins, “that also chelate metal compounds from solutions.” Id. The Examiner finds that: Given that [Curello] acknowledges that triaminetetracetic acid resins are commercially available and are effective in removing copper and nickel from solutions one of ordinary skill in the art desiring to remove these metal compounds from a solution would have a reasonable expectation of success to substitute the analogous functionalized resin of Zimmerman with the triaminetetracetic acid resin of [Curello], and one of ordinary skill in the art would be motivated to do so because the triaminetetracetic acid resin of [Curello] is effective at removing the desired metals, copper and nickel. Id. at 9. Appellant argues that Curello is non-analogous art because it is not: “(1) directed to the same field of endeavor as Applicant’s invention; or (2) reasonably pertinent to the particular problem with which the inventors [are] concerned.” App. Br. 4 (citing In re Deminski, 796 F.2d 436, 442 (Fed. Cir. 1986)). Appellant argues that the invention’s field of endeavor is treating “a protein-enriched material derived from a plant to ‘clean’ the material (e.g., rendering it more suitable as an edible material).” Id. at 5 (emphasis omitted). Appellant argues, in contrast, Curello’s “fuel cell/cartridge which can scavenge metals from fuel in contact therewith (as taught in the Curello reference) is in a completely different field of endeavor.” Id. Appellant argues Curello is not “reasonably pertinent” because Curello uses a resin to remove components from fuel thereby minimizing internal pressure inside Appeal 2019-004466 Application 14/878,561 6 fuel liners and cartridges, not to provide a purer protein-based material. Id. at 5–6. We are not persuaded. We focus our discussion on the Examiner’s finding that Curello is “reasonably pertinent to the particular problem with which the inventor is involved.” See In re Clay, 966 F.2d 656, 658–59 (Fed. Cir. 1992). Our reviewing court has held that: A reference is reasonably pertinent if … it is one which, because of the matter with which it deals, logically would have commended itself to an inventor's attention in considering his problem. If a reference disclosure has the same purpose as the claimed invention, the reference relates to the same problem, and that fact supports use of that reference in an obviousness rejection. Sci. Plastic Prod., Inc. v. Biotage AB, 766 F.3d 1355, 1359 (Fed. Cir. 2014) (internal citations omitted). “[W]hen the problem an invention is designed to solve is not unique to the specific field of the invention, it is not improper for the trier of fact to consider whether a person of ordinary skill would consult a different art in order to solve the problem.” Id. at 1360. In Scientific Plastic Products, the invention at issue claimed “[a] low pressure liquid chromatographic cartridge,” which was in a different field of endeavor from the cited prior art directed to “‘soda-pop’ bottle caps.” Id. Our reviewing court found that the prior art bottle cap references “address[ed] the problem of providing a fluid tight seal at elevated pressures, between a container and a resealable cap. This is sufficiently close to the problem addressed by the claimed invention.” Id. Appellant’s invention solves the problem of removing metal contaminants from a solution. This problem is not unique to the specific Appeal 2019-004466 Application 14/878,561 7 field of the invention, viz., plant proteins. Zimmerman and Curello teach functionalized resins for removing contaminants from solutions applicable across a wide-range of technology. For example, Zimmerman teaches “[a]ny adsorbent material possessing a combination of characteristics illustrated by these examples, i.e., a porous material comprising a metal selective chelating functionality, can be a metal selective adsorption agent within the scope of the methods described herein provided it has an appropriate adsorptivity and selectivity.” Zimmerman ¶ 33. Curello teaches removing contaminants from fuel with: “(a) suitable scavengers of oxygen, (b) suitable scavengers of carbon dioxide, (c) suitable scavengers of transition metals, (d) suitable desiccants of water, or (e) combinations thereof.” Curello ¶ 29. Curello teaches “[s]cavengers of oxygen have been used as additives to the water used to make steam in the food processing industry.” Id. ¶ 30. Accordingly, Curello suggests consulting other fields of technology to solve the problem of removing contaminants from a fuel solution. With respect to the claimed “resin functionalized with a chelating group selected from the group consisting of triaminetetraacetic acid groups, salts thereof, and combinations thereof,” Curello specifically teaches “[s]cavengers of transition metals can include, but are not limited to, functionalized silicon-containing compounds, such as those commercially available from Silicycle.” Curello ¶ 49. Curello lists the claimed compounds specifically, and incorporates the SiliCycle “Metal Scavenger Selection Guide” website in its entirety. Id. Appeal 2019-004466 Application 14/878,561 8 The SiliCycle website, dated October 2005,2 (“2005 SiliCycle”) teaches “SiliCycle has a wide range of scavengers that can remove a variety of transition metal.” 2005 SiliCycle 1. 2005 SiliCycle teaches Si-TAAcOH scavenges Pd(0), and Ni(0) and Si-TAAcONa scavenges Pd(II), Ni(II), and Cu(II). Id. at 1–2. The 2012 SiliCycle website (“2012 SiliCycle”) teaches that silica bound metal scavengers are available in “a wide range of formats for all purification scales from laboratory to plant purifications.” 2012 SiliCycle 3. 2012 SiliCycle teaches “SiliaMetS® TAAcONa or (or SiliaMetS Triaminetetraacetate, sodium salt) is a silica bound metal scavenger for Pd(II), Ni(II) and Cu.” Id. at 2. 2012 SiliCycle teaches SiliaMetS® TAAcOH (SiliaMetS Triaminetetraacetic Acid) is a silica bound metal scavenger for Pd(0), Ni(0) and Cu. Id. at 4. Furthermore, 2012 SiliCycle is not limited to any particular field of purification, and teaches functionalized metal chelators having broad applicability. It would have been obvious for one of ordinary skill in the art to combine porous materials comprising a metal-selective chelating 2 Curello was filed on October 5, 2005 as Application No. 11/243,766. The application was submitted with a printout of the SiliCycle Website as of October 5, 2005 (“2005 SiliCycle”). This version of the website is no longer available. The 2012 SiliCycle website listed similar information and is available as archived versions. See SiliCycle, SiliaMetS® - Metal Scavengers, https://web.archive.org/web/20120721204350/ https://www.silicycle.com/products/metal-scavengers, and SiliCycle, SiliaBond® - Functionalized Silica Gels, https://web.archive.org/web/ 20120504162706/http://www.silicycle.com/products/functionalized-silica- gels, both accessed May 5, 2020 (“2012 SiliCycle”). Appeal 2019-004466 Application 14/878,561 9 functionality taught by Curello and 2012 SiliCycle with Zimmerman for the reasons given by the Examiner. However, because 2012 SiliCycle was not cited by the Examiner in the Final Office Action, we designate our decision as a New Ground of affirmance. NEW GROUND OF REJECTION We here enter a new ground of rejection. Claim 40 is unpatentable under 35 U.S.C. § 103 as being obvious over Zimmerman and 2012 SiliCycle. As discussed supra, Zimmerman teaches receiving a plant-derived protein-enriched material comprising one or more heavy metals, dissolving the material to form a solution and contacting the solution with a functionalized resin to reduce the amount of heavy metal. Zimmerman’s process uses commercially available metal-chelating functionalized resins. See Zimmerman ¶¶ 32–33, 67–69. 2012 SiliCycle teaches that Si-TAAcOH and Si-TAAcONa functionalized resins were commercially available products used for chelating one or more of nickel and copper. See 2012 SiliCycle 1–4. It would have been obvious for one of ordinary skill in the art to modify Zimmerman’s functionalized resins with the commercially available SiliCycle functionalized resins. “If a person of ordinary skill can implement a predictable variation [of a known work], § 103 likely bars its patentability.” KSR Int’l Co. v. Teleflex Inc., 550 U.S. 398, 417 (2007). We have entered a new ground for only the independent claim and leave it to the Examiner to evaluate the patentability of the other claims in view this combination with other newly found or previously cited references by identifying the claimed elements in the prior art. Appeal 2019-004466 Application 14/878,561 10 Issue 2 Appellant argues one of skill in the art would have no reasonable expectation of success in combining Zimmerman and Curello. App. Br. 7. Analysis Appellant argues that “one of skill in the art would … have no reasonable expectation of success in employing a resin taught to be useful in the construction of a polymer-based shell of a fuel cartridge to treat an edible protein-based material to clean the material.” App. Br. 7. Appellant argues that Zimmerman and Curello teach “two fundamentally different environments [that] cannot be equated.” Id. Specifically, Appellant argues Curello teaches metal scavenging in a fuel environment as opposed to Zimmerman’s aqueous environment. Id. We are not persuaded. As discussed above, Zimmerman teaches removing soluble metal ions from aqueous tobacco extracts by incorporating various metal chelating agents based on appropriate adsorptivity and selectivity. Zimmerman ¶ 33. Curello and the SiliCycle website teach that Si-TAAcOH and Si-TAAcONa have specific selectivity for palladium, nickel, and copper. See Curello ¶ 49, Table 1; See 2005 SiliCycle; 2012 SiliCycle. The references do not limit the field of use of the metal chelating agents, rather, the references teach broad applicability. Accordingly, we agree with the Examiner that a person of ordinary skill in the art would have had a reasonable expectation of success combining Zimmerman and Curello to obtain protein concentrate having a reduced amount of one or more of copper, cadmium, lead, and nickel. Appeal 2019-004466 Application 14/878,561 11 Issue 3 Appellant argues that the Specification includes objective evidence of nonobviousness in the form of surprising results. App. Br. 8. Analysis Appellant argues that Example 9 of the Specification discloses that “[t]he particular resins specifically recited in the pending claims, which are functionalized with triaminetetraacetic acid and triaminetetraacetate, sodium salt groups were, as noted in the application as filed, found to be of particular importance in reducing the metals to desirable levels.” App. Br. 8 (emphasis omitted). Appellant argues that: [T]he Experimental data provided in the present application demonstrates that a chelating resin with polyamine functionality, a resin with porous styrene DVB polymer matrix with sulfonic acid groups, and a silica gel resin functionalized with imidazole group all led to no change in the total content of cadmium, copper, lead, or nickel. Surprisingly, only the recited resin (a resin functionalized with triaminetetraacetic acid and/or triaminetetraacetate salts) led to a decrease in the content of these metals. Id. The Examiner responds that the unexpected results are not commensurate with the scope of the claims. Ans. 10. The Examiner finds “the claims only require one or more of copper, cadmium, lead, and nickel, and requires no heating of the mixture.” Id. In contrast, the Examiner finds that Table 1 of the Specification shows that the “unexpected result only Appeal 2019-004466 Application 14/878,561 12 occurred with the removal of copper by triaminetetracetic acid groups after heating the mixture at 60°C prior to metal removal.” Id. Appellant responds that Table 1 of the Specification “explicitly shows: a) a reduction of all four metals recited in the pending claims (namely, copper, cadmium, lead, and nickel); and b) that such reductions were obtained in the presence of heating and in the absence of heating.” Reply Br. 2 (citing Spec. 31–32). Appellant argues that the results support the entire claimed range and thus, the results are commensurate with the scope of the claims. Id. at 2–3. We are not persuaded. “If an applicant demonstrates that an embodiment has an unexpected result and provides an adequate basis to support the conclusion that other embodiments falling within the claim will behave in the same manner, this will generally establish that the evidence is commensurate with [the] scope of the claims.” In re Kao, 639 F.3d 1057, 1068 (Fed. Cir. 2011). We begin with the scope of Appellant’s claims. We agree with the Examiner that the scope of the claims is broader than the allegedly unexpected results shown in the Specification. First, claim 40 does not require any heat or minimum contact time between the solution and the resin. App. Br. 12. Second, claim 40 recites “the functionalized resin comprises a resin functionalized with a chelating group selected from the group consisting of triaminetetraacetic acid groups, salts thereof, and combinations thereof.” Id. Accordingly, the claim allows for the use of a single triaminetetraacetic acid resin. We next consider Appellant’s evidence of unexpected results. The Specification’s Example 9(a)–(c) provides comparative tests of mixing Appeal 2019-004466 Application 14/878,561 13 protein concentrate with various resins and shaking the resultant mixture for 1 hour. See Spec. 30–31. The Specification discloses that treatment with these resins “provided no change in the total content of cadmium, copper, lead, or nickel.” Id. Example 9(d) describes numerous tests using a combination of TAAcOH and TAAcONa functionalized resins. Spec. 31–32. The Specification explains that “[a]ccording to the manufacturer, higher scavenging rates can sometimes be achieved at higher shake times and/or increased temperature; therefore, these parameters were modified to evaluate the effect of each.” Id. at 31, ll. 20–22. Notably, the tests included shaking the protein-resin mixture for 3 or 6 hours rather than 1 hour, or heating the mixture at 60° C without shaking for 3 or 6 hours. Id. at 31, ll. 23–30. “The greatest reduction in metal content was achieved with the TAAcOH/TAAcONa resins by heating the mixture at 60 °C or with the TAAcOH/TAAcONa by shaking the mixture for 3 hours. These treatments reduced the majority of the metals by greater than 50%.” Id. at 32, ll. 1–4. Table 1 reports the results of these two tests only. See id. 32, ll. 6–10. The results of Table 1 do not provide an adequate basis to support the conclusion that other embodiments falling within the claim will behave in the same manner. Appellant’s own results indicate that both temperature and contact time affect metal removal. For example, a contact time of 1 hour appears to cause no change in the total metal content. See Spec. 30–31. However, the claims do not require any minimum temperature or contact time between the protein concentrate and the resin. See App. Br. 12–14. Likewise, Appellant does not report testing with only one of the TAAcOH or TAAcONa resins. See Spec. 31–32. However, the scope of the Appeal 2019-004466 Application 14/878,561 14 claims encompass using the resins individually. See supra. The reported results do not provide an adequate basis to support the conclusion that embodiments using a single TAAcOH or TAAcONa resin, with shaking times of 1 hour and no heat will behave in the same manner. Accordingly, the results are not commensurate with the scope of the claims. The parameters of the comparative examples, i.e., 1 hour of shaking with no heat, indicates that the experimental results are not compared to the closest prior art. “[W]hen unexpected results are used as evidence of nonobviousness, the results must be shown to be unexpected compared with the closest prior art.” In re Baxter Travenol Labs., 952 F.2d 388, 392 (Fed. Cir. 1991). For example, Zimmerman teaches that contacting protein concentrates with absorbent resins for 24 hours at 60° C under gentle agitation caused 78.91% and 33.46% reduction in cadmium for various resins. See Zimmerman ¶¶ 68–70. Zimmerman’s increased contact time and heating is a more relevant comparison than the comparative examples lacking both. Additionally, none of the comparative examples in the Specification applied combinations of resins, unlike Example 9(d). See Spec. 30–32. However, Zimmerman teaches a combination of resins reduces cadmium by 58.71% and lead by 22.41%. See Zimmerman ¶ 71. Again, Zimmerman’s combination of resins is closer prior art, and, unsurprisingly, successfully removes metals unlike Appellant’s comparative examples. Because the allegedly unexpected results are not compared to the closest prior art and are not commensurate with the scope of the claims, the evidence as a whole supports the Examiner’s rejection. Appeal 2019-004466 Application 14/878,561 15 Issue 4 Appellant argues that claims 65 and 66 are separately patentable because they claim significantly improved metal reduction. App. Br. 9. Analysis Claims 65 and 66 recite specific amounts of metal reduction, e.g., at least 25% (claim 65) and at least 50% (claim 66). App. Br. 13–14. The Examiner finds the claims recite optimized ranges discoverable by routine experimentation. Final Act. 8. The Examiner finds Appellant has not provided evidence showing that the claimed amounts are critical. Id. The Examiner determines that the claims would have been obvious because “one of ordinary skill in the art would desire to optimize the extraction process of Zimmerman in order to maximize the amount of metals removed from the tobacco extract.” Id. Appellant argues that “one of skill in the art would have no reasonable expectation of success in so significantly improving metal reduction to the recited values” of claims 65 and 66. App. Br. 9. Although Appellant acknowledges that Zimmerman teaches using functionalized resins to remove up to 78.91% cadmium and up to 77.52% lead, Appellant argues that “[t]his demonstrates that results for different metals and for different types of resins can vary widely.” Id. at 9–10 (emphasis omitted). Appellant argues “[o]ne of skill in the art is provided with no motivation to optimize a particular type of resin (e.g., a chelating resin) based on these findings and is provided with no means for arriving at the specific reductions recited in claims 65 and 66.” Id. Appeal 2019-004466 Application 14/878,561 16 We are not persuaded. The evidence directly contradicts Appellant’s argument. Zimmerman, Curello, and the SiliCycle website all teach choosing functionalized resins based on “appropriate adsorptivity and selectivity.” See Zimmerman ¶ 33. Zimmerman teaches that “a soluble metal selective adsorption agent … will preferably have an adsorptivity index greater than about 60.” Id. ¶ 34. Curello and the SiliCycle website teach that Si-TAAcOH and Si-TAAcONa functionalized resins have specific selectivity for copper and nickel, two of the “one or more” metals recited by claims 65 and 66. Curello ¶ 49. In sum, the prior art teaches that identifying and removing specific metals is a result-effective variable that may be optimized by choosing specific functionalized resins or combinations thereof. Accordingly, we are not persuaded that the Examiner erred in determining claims 65 and 66 would have been obvious over the combined prior art. We consequently affirm the Examiner’s rejection of the claims. CONCLUSION The rejection of claims 40, 53–59 and 62–66 as unpatentable under 35 U.S.C. § 103 is affirmed. We enter a NEW GROUND of rejection. Claim 40 stands rejected as unpatentable under 35 U.S.C. § 103 as being obvious over Zimmerman and 2012 SiliCycle. 37 C.F.R. § 41.50(b) provides that “[a] new ground of rejection … shall not be considered final for judicial review.” 37 C.F.R. § 41.50(b) also provides that Appellant, WITHIN TWO MONTHS FROM THE DATE OF THE DECISION, must exercise one of Appeal 2019-004466 Application 14/878,561 17 the following two options with respect to the new ground of rejection to avoid termination of the appeal as to the rejected claims: (1) Reopen prosecution. Submit an appropriate amendment of the claims so rejected or new evidence relating to the claims so rejected, or both, and have the matter reconsidered by the examiner, in which event the prosecution will be remanded to the examiner …. (2) Request rehearing. Request that the proceeding be reheard under § 41.52 by the Board upon the same record. No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a)(1). See 37 C.F.R. § 1.136(a)(1)(iv). AFFIRMED 37 C.F.R. § 41.50(b) Claims Rejected 35 U.S.C. § Reference(s)/Basis Affirmed Reversed New Ground 40, 53– 59, 62–66 103 Zimmerman, Garger, Curello 40, 53– 59, 62–66 40 103 Zimmerman, 2012 SiliCycle 40 Overall Outcome 40, 53– 59, 62–66 40 Copy with citationCopy as parenthetical citation