Ex Parte Wiemker et alDownload PDFPatent Trial and Appeal BoardJun 25, 201815304932 (P.T.A.B. Jun. 25, 2018) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 15/304,932 10/18/2016 Rafael WIEMKER 24737 7590 06/27/2018 PHILIPS INTELLECTUAL PROPERTY & STANDARDS 465 Columbus A venue Suite 340 Valhalla, NY 10595 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 2014P00172WOUS 8506 EXAMINER WILLS, DIANE M ART UNIT PAPER NUMBER 2617 NOTIFICATION DATE DELIVERY MODE 06/27/2018 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address( es): patti. demichele@Philips.com marianne.fox@philips.com katelyn.mulroy@philips.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte RAFAEL WIEMKER, TOBIAS KLINDER, and THOMAS BUELOW Appeal2018-005459 Application 15/304,932 1 Technology Center 2600 Before CARLA M. KRIVAK, HUNG H. BUI, and JON M. JURGOV AN, Administrative Patent Judges. BUI, Administrative Patent Judge. DECISION ON APPEAL Appellants seek our review under 35 U.S.C. § 134(a) of the Examiner's Final Rejection of claims 1-5, 13, 14, and 20, 2 which are all the claims pending in the application. Claims App 'x. We have jurisdiction under 35 U.S.C. § 6(b). We REVERSE. 3 1 According to Appellants, the real party in interest is Koninklijke Philips N.V. App. Br. 2. 2 Claims 6-12 and 15-19 are conditionally allowed if rewritten in independent form including all the limitations of the base claims and any intervening claims. App. Br. 7. 3 Our Decision refers to Appellants' Appeal Brief ("App. Br.") filed January 2, 2018; Reply Brief ("Reply Br.") filed April 30, 2018; Examiner's Answer ("Ans.") mailed March 8, 2018; Final Office Action ("Final Act.") mailed August 10, 2017; and original Specification ("Spec.") filed October 18, 2016. Appeal2018-005459 Application 15/304,932 STATEMENT OF THE CASE Appellants' invention relates to "visualize[ ation] of tissue of interest in contrast-enhanced image data" in the context of "computed tomography (CT)[,]. .. magnetic resonance (MR), ultrasound (US) and/or other three dimensional (3D) imaging modalities with contrast enhanced imaging capabilities" used for pulmonary embolism (e.g., patients with chest pain) inspection and detection, particularly, in hypo-dense areas (locations) such as pulmonary arteries. Spec. 1: 1-17. According to Appellants, "an image processing approach" is utilized "to generate a rendering that highlights suspected presence and locations of pulmonary embolisms in contrasted- enhanced volumetric image data" and "[t]he enhancement ... is achieved by a combination of a vessel filter [ 402, shown in Figure 4] and a hypo-density filter [ 404]." Spec. 2: 12-15. Appellants' Figure 4 is reproduced below: 324 ~ Image data processor module Appellants' Figure 4 shows image data processor module 324 including vessel filter 402 and hypo-density filter 404. 2 Appeal2018-005459 Application 15/304,932 As shown in Appellants' Figure 4, vessel filter 402 is arranged to process each voxel of image data and produce a vesselness value for each voxel. Hypo-density filter 404 is arranged to process each voxel of image data and produce a hypo-density value for each voxel based on image data and iso-surfaces that yield the maximum value of the vesselness for the voxel at a particular location. Spec. 5:31-34, 7: 14--19. Claims 1, 14, and 20 are independent. Claim 1 illustrates the claimed subject matter, as reproduced below with disputed limitations in italics: 1. A method, comprising: obtaining contrast-enhanced image data having a plurality of voxels, each voxel having an intensity value; determining a vesselness value for each voxel; determining a hypo-density value for each voxel; weighting each of the intensity values by a corresponding vesselness value; weighting each of the hypo-density values by the corresponding vesselness value; combining the weighted intensity values and the weighted hypo-density values, thereby generating composite image data; and visually displaying the composite image data. App. Br. 6 (Claims App'x). REJECTION AND REFERENCES Claims 1-5, 13, 14, and 20 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over Wiemker et al. (US 2012/0093390 Al; published April 19, 2012) ("Wiemker I") and Wiemker et al. (US 2010/0074493 Al; published Mar. 25, 2010) ("Wiemker II"). Final Act. 3-7. 3 Appeal2018-005459 Application 15/304,932 ANALYSIS In support of the obviousness rejection, the Examiner finds the combination of Wiemker I and Wiemker II teaches all limitations of independent claim 1, and similarly, claims 14 and 20. Final Act. 3-5. For example, the Examiner finds Wiemker I teaches Appellants' method, including: "obtaining contrast-enhanced image data having a plurality of voxels, each voxel having an intensity value;" "determining a vesselness value for each voxel;" "weighting each of the intensity values by a corresponding vesselness value;" and "visually displaying the composite image data." Final Act. 3--4 (citing Wiemker I i-fi-144, 48). To support the conclusion of obviousness, the Examiner finds Wiemker II further teaches the missing steps from Wiemker I, including: "determining a hypo-density value for each voxel;" "weighting each of the hypo-density values by the corresponding vesselness value;" and "combining the weighted intensity values and the weighted hypo-density values, thereby generating composite image data." Final Act. 4 (citing Wiemker II i-fi-157-58, 62). Thus, according to the Examiner, Wiemker I teaches "determining the vesselness value and using it to weight each intensity value of a CT image" while Wiemker II teaches "weighting hypo- density values (minimum encountered on the path so far) by a corresponding vesselness value (the value of the distance map at the current point)." Id. at 4 (citing Wiemker II i144). Appellants do not dispute the Examiner's findings regarding Wiemker I or the Examiner's reason for the combination. Instead, Appellants contend Wiemker II does not teach or suggest any hypo-density value determination for each voxel [of contrast-enhanced image data], including the disputed 4 Appeal2018-005459 Application 15/304,932 limitations: "determining a hypo-density value for each voxel;" "weighting each of the hypo-density values by the corresponding vesselness value;" and "combining the weighted intensity values and the weighted hypo-density values, thereby generating composite image data" recited in claim 1 and similarly recited in claims 14 and 20. App. Br. 3-5. Particularly, Appellants argue the cited paragraph 62 of Wiemker II only describes computing a deficiency value associated with a position along a vascular structure that is indicative of a difference between (1) a filling value of a position and (2) a minimum filling value of that position. App. Br. 4 (citing Wiemker II i-f 62). According to Wiemker II, ( 1) the filling value is defined as an amount of blood at a position/voxel along a central axis of a vessel, and (2) the minimum filling value is defined as a smallest amount of blood at a position/voxel on the path upstream from a given position/voxel on the path. App. Br. 4 (citing Wiemker II i-fi-1 6, 4 7, 60, 61 ). Based on the definition of Wiemker II's "deficiency value," Appellants argue (1) "the term hypo- density is defined in the subject application in Equation 3" and (2) "[i]nterpreting the claimed hypo-density as merely any difference [in an amount of blood at two voxels] is unreasonably broad in view of Equation 3. ,, A B 4 pp. r .. In response, the Examiner takes the position that: ( 1) "the term 'hypo- density' has a broader meaning in the art, and needs to be more clearly defined in the claims"; (2) the meaning of "hypo-density" "derived from Equation 3 described in pages 3 and 4 of the specification, but the language of the specification is not in the claims, nor is it proper to import limitations from the specification into the claims"; (3) "the claim language 'determining a hypo-density value for each voxel' does not require that 5 Appeal2018-005459 Application 15/304,932 Equation 3 be used to calculate hypo-density, just that some measure of hypo-density is disclosed" and, as such, (4) "hypo-density can be broadly interpreted as meaning any calculation of hypo-density," including a deficiency value for each vascular structure position as described by Wiemker II's paragraph 62. Ans. 2. We agree with the Examiner only in part-that (1) "the term 'hypo- density' has a broader meaning in the art" and (2) it is improper to read a limitation (e.g., Equation 3) from the specification into the claims, In re Van Geuns, 988 F.2d 1181, 1184 (Fed. Cir. 1993). However, the term "hypo- density," albeit given its broadest reasonable interpretation, must still be interpreted consistent with Appellants' Specification. In re Am. A cad. of Sci. Tech Ctr., 367 F.3d 1359, 1364 (Fed. Cir. 2004). "[T]he proper BRI construction is not just the broadest construction, but rather the broadest reasonable construction in light of the specification." In re Man Mach. Interface Techs. LLC, No. 2015-1562, 2016 WL 1567181, at *3 (Fed. Cir. 2016) (citing Microsoft Corp. v. Proxyconn, Inc., 789 F.3d 1292, 1298 (Fed. Cir. 2015)) ("A construction that is 'unreasonably broad' and which does not 'reasonably reflect the plain language and disclosure' will not pass muster."). In this case, the term "hypo-density" is not expressly defined in Appellants' Specification; however, the ordinary meaning of the word "hypo" is "less than normal." See Webster's II New College Dictionary. The term "hypo-density" is described by Appellants' Specification in the context of (1) "hyper-dense areas in normally contrast-agent filled pulmonary arteries" (Spec. 1: 16-20); (2) "pulmonary embolisms may be manifest because they be a lower density than the normal vessel ... a higher 6 Appeal2018-005459 Application 15/304,932 HU than the surrounding parenchymal or mediastinal tissue" (Spec. 2: 1--4 ); (3) "enhancement [] achieved by a combination of a vessel filter and a hypo- filter" "to generate a rendering that highlights suspected presence and locations of pulmonary embolisms in contrasted-enhanced volumetric image data" (Spec. 2:12-15); (4) the difference a vesselness value of each voxel and a hypo-density value for each voxel (Spec. 5:31-8:5); and (5) how the hypo-density filter 404 is used to process each voxel of the volumetric image data I(x), independently, in connection with an iso-surface corresponding thereto and to produce, for each voxel, a scalar hypo-density feature vector H(x) based on the volumetric image data I(x) and the iso-surfaces S(T) that yielded the maximum value of VT (Spec. 7: 14--19). As such, when viewed in light of Appellants' Specification, we agree with Appellants that the term "hypo-density value for each voxel" cannot be broadly interpreted to encompass Wiemker II' s disclosure of "a deficiency value" associated with a position along a vascular structure that is indicative of a difference between (1) a filling value of a position and (2) a minimum filling value of that position, where respective filling values represent an amount of blood in a neighborhood of the respective position in the vascular structure. Reply Br. 2; see also Wiemker II i-fi-1 6, 11, 60-62. Separately, we also note that (1) nowhere in Wiemker II is there any teaching or suggestion of "hyper-density" or pulmonary embolism inspection of hypo-dense areas or "hypo density" locations, and (2) the Examiner's rationale to incorporate the teachings of Wiemker II into Wiemker I, i.e., "the results of the combination were predictable" is without any "rational underpinning" as required by KSR Int 'l Co. v. Teleflex, Inc., 550 U.S. 398, 418 (2007); andin re Kahn, 441F.3d977, 988 (Fed Cir. 7 Appeal2018-005459 Application 15/304,932 2006) ("[R ]ejections on obviousness grounds cannot be sustained by mere conclusory statements; instead, there must be some articulated reasoning with some rational underpinning to support the legal conclusion of obviousness."). For these reasons, we do not sustain the Examiner's rejection of independent claim 1 and claims 2-5, and 13 dependent therefrom. We also do not sustain the Examiner's rejection of independent claims 14 and 20, argued for the same reasons as claim 1 (App. Br. 5). CONCLUSION On the record before us, we conclude Appellants have not demonstrated the Examiner erred in rejecting claims 1-5, 13, 14, and 20 under 35 U.S.C. § 103(a). DECISION As such, we reverse the Examiner's Final rejection of claims 1-5, 13, 14, and 20 under 35 U.S.C. § 103(a). REVERSED 8 Copy with citationCopy as parenthetical citation