Ex Parte Sharpe et alDownload PDFPatent Trial and Appeal BoardFeb 20, 201814030946 (P.T.A.B. Feb. 20, 2018) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/030,946 09/18/2013 Johnathan Charles Sharpe 118153-05002 8133 106574 7590 02/22/2018 McCarter & English / Cytonome/ST, LLC 265 Franklin St. Boston, MA 02110 EXAMINER KWAK, DEAN P ART UNIT PAPER NUMBER 1798 NOTIFICATION DATE DELIVERY MODE 02/22/2018 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): docket @ mccarter.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte JOHNATHAN CHARLES SHARPE, RUDOLF HULSPAS, and KRISTOPHER SCOTT BUCHANAN Appeal 2017-005705 Application 14/030,946 Technology Center 1700 Before MICHAEL P. COLAIANNI, DONNA M. PRAISS and MERRELL C. CASHION, JR., Administrative Patent Judges. CASHION, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF THE CASE This is an appeal under 35 U.S.C. § 134 from a final rejection of claims 1, 2, 4, 7, 9, 11-13, 15-17, 30, and 31. We have jurisdiction under 35 U.S.C. § 6. We AFFIRM-IN-PART. Appeal 2017-005705 Application 14/030,946 Claim 1 is illustrative of the subject matter on appeal and is reproduced below: 1. A flow cell for processing particles in a stream, comprising: an enclosed sort chamber including a first plurality of fluid contact surfaces forming a plurality of regions in fluid communication with one another, the fluid contact surfaces defining: a stream focusing region; an orifice located downstream of the focusing region; a particle interrogation region located downstream of the orifice; and a droplet deflection region, wherein the fluid contact surfaces of the sort chamber are integrally constructed, wherein the sort chamber includes at least one surface transmissible to electromagnetic radiation from an excitation source, and wherein the flow cell is operatively sealed. Appellant1 requests review of the Examiner’s rejection of claims 1, 2, 4, 7, 9, 11-13, 15-17, 30, and 31 under 35 U.S.C. § 102(b) as anticipated by Hall (US 2003/0138967 Al, published July 24, 2003). Final Act. 2; App. Br. 6. 1 Cytonome/ST, LLC is the Applicant and is also identified as the real party in interest. App. Br. 2. 2 Appeal 2017-005705 Application 14/030,946 OPINION After review of the respective positions provided by Appellant and the Examiner, we AFFIRM the Examiner’s prior art rejection of claims 1, 7, 12, 13, 16, 30, and 31 for the reasons presented by the Examiner. However, we REVERSE the Examiner’s prior art rejection of claims 2, 4, 9, 11, 15, and 17 for the reasons presented by Appellant. We add the following for emphasis. As a preliminary matter, we first address Appellant’s argument as to the interpretation of the language “integrally constructed” in claims 1, 2, and 4. App. Br. 9 (footnote 1); Reply Br. 4-5. “[Djuring examination proceedings, claims are given their broadest reasonable interpretation consistent with the specification.” In re Translogic Tech., Inc., 504 F.3d 1249, 1256 (Fed. Cir. 2007) (quoting In re Hyatt, 211 F.3d 1367, 1372 (Fed. Cir. 2000)). See also In re Am. Acad. ofSci. Tech Ctr., 367 F.3d 1359, 1364 (Fed. Cir. 2004) (The scope of the claims in patent applications is not determined solely on the basis of the claim language, but upon giving claims their broadest reasonable construction in light of the specification as it would be interpreted by one of ordinary skill in the art.) (citations omitted); Phillips v. AWHCorp., 415 F.3d 1303, 1315 (Fed. Cir. 2005) (“[T]he specification ‘is always highly relevant to the claim construction analysis. Usually, it is dispositive; it is the single best guide to the meaning of a disputed term.’” (Citation omitted)). We agree with Appellant that the term “integrally constructed” is to be interpreted as defined in paragraph 36 of the Specification. App. Br. 9 (footnote 1); Reply Br. 4-5. That is, the language recited in independent claim 1 “the fluid contact surfaces of the sort chamber are integrally 3 Appeal 2017-005705 Application 14/030,946 constructed” describes fluid contact surfaces that are “in a permanent, structural relationship as a single unit.” Spec. ^ 36. In addition, we interpret the term “fluid contact surfaces” in claim 1 as “reservoirs, tubes, chambers, vessels, nozzles, orifices, fittings and/or other elements which contact and/or are exposed to fluid in the flow cell.” Spec. ^ 31. Claims 1, 7, 12, 13, 16, 30, and 31 Wq AFFIRM. Appellant presents arguments for claims 1,16, 30, and 31. See generally App. Br. Appellant does not present separate arguments for claims 7, 12, and 13. Id. We address the claims argued. However, claims 7, 12, and 13 stand or fall with independent claim 1, from which they depend. Claim 1 Claim 1 is directed to a flow cell comprising an enclosed chamber including a plurality of fluid contact surfaces integrally constructed. The Examiner finds Hall discloses a flow cell comprising a sort chamber 16 having a plurality of fluid contact surfaces integrally constructed as claimed. Final Act. 2—4; Hall Figure 2, 33^40, 45. We note the fluid contact surfaces in Hall that contact or are exposed to the fluid are principally the surfaces of component 2 enclosed by chamber 16 as well as the internal surfaces of chamber 16. Hall Figure 2. Appellant argues that Hall does not provide any construction details for the device in Figure 2 and, thus, fails to disclose that Hall’s item 7 or 4 Appeal 2017-005705 Application 14/030,946 Hall’s item 14 has fluid contact surfaces integrally constructed (or even "constructed as a whole") with Hall’s item 6 or Hall’s item 2. App. Br. 10. We are unpersuaded of error for the reasons presented by the Examiner. Final Act. 2-3. In order to anticipate, a reference must identify something falling within the claimed subject matter with sufficient specificity to constitute a description thereof within the purview of § 102. In re Schaumann, 572 F.2d 312, 317 (CCPA 1978). It is well established that specific examples of the claimed subject matter are not necessary to establish anticipation. Rather, to anticipate, one skilled in the art must be able to “at once envisage” the claimed subject matter in the prior art disclosure. In re Petering, 301 F.2d 676, 681 (CCPA 1962). Further, in determining whether a reference anticipates the subject matter recited in a claim, “it is proper to take into account not only specific teachings of the reference but also the inferences which one skilled in the art would reasonably be expected to draw therefrom.” In re Preda, 401 F.2d 825, 826 (CCPA 1968). Hall’s Figure 2 shows a flow cell having fluid contact surfaces which contact and/or are exposed to fluid in the flow cell that are in a structural relationship as a single unit. A person of ordinary skill would have drawn a reasonable inference from HalFs Figure 2 that the fluid contact surfaces in Hall’s Figure 2 are in a permanent, structural relationship (that is, integrally constructed). While Appellant asserts Hall’s Figure 2 is a diagrammatic representation of the flow cell lacking construction details (App. Br. 10), Appellant directs us to no portion of Hall or provide any other objective evidence that supports this assertion. Appellant, at most, has provided mere attorney arguments and such arguments of counsel cannot take the place of 5 Appeal 2017-005705 Application 14/030,946 evidence. See In re De Blauwe, 736 F.2d 699, 705 (Fed. Cir. 1984); In re Payne, 606 F.2d 303, 315 (CCPA 1979). Appellant argues Hall expressly discloses that different models of flow cytometers from various manufacturers may be accommodated by enclosure 26. App. Br. 11; Hall ^ 41. According to Appellant, items 2, 6, 7 and 14 of Hall’s device are provided separately and inserted into enclosure 26. App. Br. 11; Hall Figures 2 and 3. We are also unpersuaded by these arguments for the reasons presented by the Examiner. Ans. 6. Moreover, Appellant does not adequately explain why the versatility of enclosure 26 for accommodating different models of flow cytometers necessarily means a flow cytometer, once selected and placed in the enclosure, would not result in the fluid contact surfaces being integrally constructed, as defined in the Specification. Claim 16 Claim 16 requires the stream focusing region to include a torsional hydrodynamic focusing region. The Examiner finds the claimed limitation does not further define a structure that distinguishes the claim from the device of the prior art. Ans. 7. According to the Examiner, the Specification defines the claimed “torsional hydrodynamic focusing region” as a region that applies forces to particles. Ans. 7; Spec. ^ 74. Appellant argues that the language of the claim provides a structural limitation not taught by Hall. App. Br. 15. We are unpersuaded by this argument for the reasons given by the Examiner. Ans. 7. Moreover, the Specification describes the torsional 6 Appeal 2017-005705 Application 14/030,946 region as a shape that may gradually taper, linearly or with a curvature, as it extends downstream. Spec. 75-76. This description relates to a conical surface labelled as surface 114b on Appellant’s Figure 10C. Hall’s Figure 2 also shows a conical surface on component 2. Thus, even assuming arguendo that the claim language provides a structural limitation, Appellant has not adequately explained how the claimed torsional region is distinguishable over the conical region shown in Hall’s component 2. Appellant has not explained why the conical region of Hall’s component 2 would not result in a region applying forces to particles. Claim 30 Claim 30 requires the flow cell to enclose all of the fluid contact surfaces. The Examiner finds the claimed limitation does not further define a structure that distinguishes the claim from the device of the prior art. Ans. 8. Appellant argues that the language of the claim provides a structural limitation not taught by Hall. App. Br. 16. We are unpersuaded by this argument for the reasons given by the Examiner. Ans. 8. Moreover, assuming arguendo that a structural limitation is claimed, Appellant has not adequately explained why one skilled in the art would not have inferred from Hall’s Figure 2 that all fluid contact surfaces are enclosed by the chamber 16. Claim 31 With respect to claim 31, the Examiner relies on Hall’s oscillation generator to meet the claimed limitation. Final Act. 4. Appellant does not 7 Appeal 2017-005705 Application 14/030,946 contest the Examiner’s finding that Hall’s oscillation generator is a surface acoustic wave generator. See generally App. Br. Accordingly, we affirm the Examiner’s prior art rejection of claims 1, 7, 12, 13, 16, 30, and 31 for the reasons presented by the Examiner and given above. Claims 2, 4, 9, 11, 15, and 17 Wq reverse. We refer to the Examiner’s Final Action for a statement of the rejection for the above noted claims. Final Act. 3-5. With respect to claims 2 and 4, we agree with Appellant that the Examiner does not point to any portion of Hall that adequately describes or infers that sample vessel 3 and sheath vessel 5 are integrally constructed as claimed. App. Br. 12-13; Final Act. 3 With respect to claim 9, we agree with Appellant that the claim limitation describes a structure to accommodate a transducer. App. Br. 14. The Examiner does not direct us to any portion of Hall that describes this feature. See generally Final Act. and Ans. Similarly, we agree with Appellant that the Examiner does not direct attention to any portion of Hall that describes the subject matter of claim 15 (flow control mechanism for a peristaltic pump). App. Br. 14-15; Final Act. 3. With respect to claims 11 and 17, we also agree with Appellant that the Examiner does not point to any portions of Hall that describe the limitations of these claims. App. Br. 14-16; see generally Final Act. and Ans. In fact, the Examiner’s reliance on paragraphs 71 and 72 for claim 17 8 Appeal 2017-005705 Application 14/030,946 appear to relate to Appellant’s disclosure as there are no such paragraphs in Hall. Final Act. 4. Accordingly, we reverse the Examiner’s prior art rejection of claims 2, 4, 9, 11, 15, and 17 for the reasons presented by Appellant and given above. ORDER The Examiner’s prior art rejection of claims 1, 7, 12, 13, 16, 30 and 31 under 35 U.S.C. § 102(b) is affirmed. The Examiner’s prior art rejection of claims 2, 4, 9, 11, 15, and 17 under 35 U.S.C. § 102(b) is reversed. TIME PERIOD No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a)(1). AFFIRMED-IN-PART 9 Copy with citationCopy as parenthetical citation