Ex Parte Kawamura et alDownload PDFPatent Trial and Appeal BoardFeb 20, 201814399992 (P.T.A.B. Feb. 20, 2018) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/399,992 11/10/2014 Kenji Kawamura TOR-14-2419 8652 35811 7590 02/22/2018 IP GROUP OF DLA PIPER LLP (US) ONE LIBERTY PLACE 1650 MARKET ST, SUITE 4900 PHILADELPHIA, PA 19103 EXAMINER KAHN, RACHEL ART UNIT PAPER NUMBER 1766 NOTIFICATION DATE DELIVERY MODE 02/22/2018 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): pto.phil@dlapiper.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte KENJI KAWAMURA, MASATERUITO, and KATSUSHIGE YAMADA Appeal 2017-005628 Application 14/399,9921 Technology Center 1700 Before LINDA M. GAUDETTE, CHRISTOPHER C. KENNEDY, and BRIAN D. RANGE, Administrative Patent Judges. RANGE, Administrative Patent Judge. DECISION ON APPEAL SUMMARY Appellant appeals under 35 U.S.C. § 134(a) from the Examiner’s decision rejecting claims 7—10 and 13—15. We have jurisdiction. 35 U.S.C. § 6(b). We REVERSE. 1 The Appellant is the applicant Toray Industries, Inc. The Appeal Brief indicates the applicant is also the real party in interest. Appeal Br. 1. Appeal 2017-005628 Application 14/399,992 STATEMENT OF THE CASE2 Appellant describes the invention as relating to a method of separating lactic acid from an aqueous lactic acid solution containing glycerol as an impurity. Spec. 1 6. The Specification explains that one known method is using an ion-exchange resin where lactic acid is adsorbed to and then eluded to the resin, but this method is not ideal because adsorbing a large amount of lactic acid requires a large amount of resin. Id. Thus, the invention seeks to instead use an ion-exchange resin that adsorbs the glycerol. Id. at 112. Claim 7, reproduced below, is the only independent claim on appeal and is illustrative of the claimed subject matter: 7. A method of producing lactic acid comprising removing glycerol from an aqueous lactic acid solution containing glycerol as an impurity using an ion-exchange resin by adsorbing the glycerol to the ion-exchange resin. Appeal Br. 7 (Claims App’x). REFERENCES The Examiner relies upon the prior art below in rejecting the claims on appeal: Powell et al. (“Powell”) Liu et al. (“Liu”) Munson et al. (“Munson”) Kimura et al. (“Kimura”) US 3,202,705 US 2005/0112737 Al US 2009/0199460 Al JP 2011-103879 Aug. 24, 1965 May 26, 2005 Aug. 13, 2009 June 2, 2011 2 In this opinion, we refer to the Final Office Action dated May 11, 2016 (“Final Act.”), the Appeal Brief filed November 2, 2016 (“Appeal Br.”), the Examiner’s Answer dated December 20, 2016 (“Ans.”), and the Reply Brief filed February 17, 2017 (“Reply Br.”). 2 Appeal 2017-005628 Application 14/399,992 REJECTIONS The Examiner maintains the following rejections on appeal: Rejection 1. Claims 7—9 and 13 under 35 U.S.C. § 103(a) as unpatentable over Powell in view of Kimura and Munson. Final Act. 2. Rejection 2. Claims 10, 14, and 15 under 35 U.S.C. § 103(a) as unpatentable over Powell in view of Kimura and Munson and further in view of Liu. Id. at 5. ANALYSIS With respect to independent claim 7, the Examiner finds that Powell discloses producing lactic acid by fermentation and then using a cation exchange resin “to remove or inactivate objectionable color forming materials.” Final Act. 2 (citing Powell). Powell refers to “conventional fermentation processes” (Powell 1:43—45), but the Examiner finds that Powell fails to specifically teach a fermenting process utilizing glycerol. Final Act. 3. The Examiner finds, however, that Kimura teaches a lactic acid production method using glycerol. Id? The Examiner also finds that Kimura teaches that glycerol remains in the culture solution after production of the lactic acid. Id. at 4. The Examiner finds that a person having ordinary skill in the art “would have had a reasonable expectation of success in utilizing a process for producing lactic acid from glycerol” in order to 3 We note that the Examiner has not established that the Kimura process (2011) was a “conventional fermentation process” at the time of Powell (August 24, 1965). As such, even if Powell were to be broadly read as teaching use of a cation exchange resin to remove any kind of impurities resulting from conventional processes known in 1965, the Examiner has not established that a person of skill would have necessarily understood that such resin could also remove any impurities resulting from more modem processes (such as glycerol as an impurity from the Kimura process). 3 Appeal 2017-005628 Application 14/399,992 provide the lactic acid-containing process liquor of Powell’s process and concludes that it would have been obvious to pass lactic acid produced from such a process through a cation exchange resin as taught by Powell. Id. With respect to claim 7’s “adsorbing the glycerol” recitation, the Examiner finds that Munson teaches an ion exchange resin that adsorbs glycerol. Id. at 4. Appellant argues that a person of skill in the art would not have had a reasonable expectation of success in applying Munson to the combination of Powell and Kimura in order to remove glycerol from an aqueous lactic acid solution having ionic components. Appeal Br. 4; see also In re Vaeck, 947 F.2d 488, 493 (Fed. Cir. 1991) (holding that reasonable expectation of success is a necessary part of proper obviousness analysis). Appellant cites Munson as well as the user’s guide and data sheet for the AMBERFITE™ BD10DRY™ (hereinafter referred to as “AMBERFITE”) to provide evidence that the AMBERLITE resin (utilized in, for example, Examples 2 and 4 of Munson (see Munson || 54, 60)) adsorbs water more than methanol and adsorbs methanol more than glycerol. Appeal Br. 5. Indeed, this resin exhibits considerable swelling in water. See, e.g., AMBERLITE USERS GUIDE, 1 (attached to Evidence Appendix of the Appeal Brief) (“Avoid contacting the media with pure methanol or water as this will cause it to swell up to 3 times in volume and the glass column can shatter if insufficient void space is left at the top of the column.”). Thus, while Munson teaches that AMBERLITE may be useful for adsorbing glycerol from hydrophobic biodiesel, it does not teach that it can also be useful in adsorbing glycerol away from an ionic, hydrophilic substance such as lactic acid. Appeal Br. 4; see also, e.g., Munson (Abstract, | 54). 4 Appeal 2017-005628 Application 14/399,992 Because of this difference between, on one hand, the Munson reference and, on the other hand, both claim 7 and the proposed Powell/Kimura combination, the Examiner clarifies in the Answer that Munson is not relied upon for a particular cation exchange resin and is not relied upon “to modify the process suggested by Powell and Kimura in any way.” Ans. 5. Rather, the Examiner uses Munson merely to establish that a cationic ion exchange resin is capable of adsorbing glycerol. Id. Because of the Examiner’s appropriately limited reliance on Munson, the Examiner has not adequately explained what particular resin the person of skill in the art would have chosen to remove glycerol from Powell/Kimura’s aqueous lactic acid. See Ans. 3 (identifying Powell as teaching “a strongly acidic cation exchange resin”). The Examiner also fails to adequately explain why a person of skill in the art would have had a reasonable expectation of success in adsorbing glycerol when making use of such resin. Reply Br. 2. Instead, for the reasons explained above, a preponderance of the evidence before us indicates that a person of skill in the art would not have reasonably expected a resin such as that identified in Munson (also a strong acid cation exchange resin, see AMBERL1TE product data sheet (attached to Evidence Appendix of the Appeal Brief)) to successfully adsorb glycerol from aqueous lactic acid. Indeed, the evidence of record indicates that a person of ordinary skill in the art would have expected such a resin to adsorb the ionic lactic acid. We therefore do not sustain the Examiner’s rejection of claim 7. We also do not sustain the Examiner’s rejection of claims 8—10 and 13—15 because each of those claims directly or indirectly depends from claim 7 and because the Examiner’s use of the Liu reference in rejecting claims 10, 14, 5 Appeal 2017-005628 Application 14/399,992 and 15 does not cure the issue discussed above. Final Act. 5—6 (citing Liu as teaching distillation of aqueous lactic acid after use of ion exchange). DECISION For the above reasons, we reverse the Examiner’s rejections of claims 7—10 and 13—15. REVERSED 6 Copy with citationCopy as parenthetical citation