Ex Parte EmlerDownload PDFPatent Trial and Appeal BoardFeb 10, 201712084608 (P.T.A.B. Feb. 10, 2017) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 12/084,608 05/06/2008 Stefan Emler 14-357-WO-US 1024 20306 7590 02/10/2017 MCDONNELL BOEHNEN HULBERT & BERGHOFF LLP 300 S. WACKER DRIVE 3 2ND FLOOR CHICAGO, IL 60606 EXAMINER WHALEY, PABLO S ART UNIT PAPER NUMBER 1631 MAIL DATE DELIVERY MODE 02/10/2017 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte STEFAN EMLER Appeal 2016-002226 Application 12/084,608 Technology Center 1600 Before JEFFREY N. FREDMAN, ROBERT A. POLLOCK, and DAVID COTTA, Administrative Patent Judges. FREDMAN, Administrative Patent Judge. DECISION ON APPEAL This is an appeal1 under 35U.S.C. § 134 involving claims to a method of identifying or classifying organism types from a target gene sequence. The Examiner rejected the claims as being directed to non-statutory subject matter. We have jurisdiction under 35 U.S.C. § 6(b). We affirm. Statement of the Case Background “[I]t is an object of the present invention to provide a computer- implemented method and a computer system for identifying organism types 1 Appellant identifies the Real Party in Interest as SmartGene GmbH (see App. Br. 1). Appeal 2016-002226 Application 12/084,608 from a target gene sequence, which system and method discriminate between trivial and significant inter-sequence differences.” (Spec. 2:23—27). The Claims Claims 2, 4—9, 28 and 29 are on appeal. Claim 28 is representative and reads as follows: 28. A method of identifying or classifying organism types from a target gene sequence, said method comprising: (i) obtaining the target gene sequence at a server, the server comprising one or more processors; (ii) providing at least one database using the server, the at least one database comprising a plurality of organism type- specific profiles associated with one or more related reference sequences, wherein each organism type-specific profile defines informative sequence regions for differentiating individual organisms, and wherein each organism type-specific profile comprises position specific information of related reference sequences; (iii) correlating the target gene sequence and the plurality of organism type-specific profiles using the server; (iv) selecting an organism type-specific profile having a highest correlation with the target gene sequence based on the position specific information of the related organism type- specific profile using the server; (v) retrieving the related reference sequences associated with the selected organism type-specific profile from the at least one database using the server; (vi) comparing the target gene sequence to the related reference sequences, and weighting the results of the comparison using weighting factors associated with the informative sequence regions using the server; (vii) determining, based on the comparison results weighted for the informative sequence regions, an optimal 2 Appeal 2016-002226 Application 12/084,608 organism type-specific reference sequence having a best match with the target gene sequence using the server; and (viii) identifying or classifying said organism types of said target gene sequence based on the optimal organism type- specific reference sequence by assigning to the target gene sequence the same organism type as the best matched organism type-specific reference sequence using the server; and (ix) communicating at least the organism type of the best matched organism type-specific reference sequence as an output of the server. (Appeal Br. 22—23.) The Issue The Examiner rejected claims 2, 4—9, 28 and 29 under 35 U.S.C. § 101 as being directed to non-statutory subject matter (Final Act. 3—4). The Examiner finds that claim 28 is “directed to methods and a computer readable medium for identifying or classifying organism types from a target sequence” (Final Act. 3). The Examiner further finds that the eight steps in the claims other than the abstract idea (using a server for providing a database, correlating obtaining gene sequences (i.e. data), comparing data and weighting the results using weighting factors, and classifying an organisms type based on “organism type-specific” reference sequences) are ALL purely computational and amount to no more than insignificant extra-solution activity that is well-understood, routine and conventional in the art and/or instructions to implement the abstract idea on a generic server. (Final Act. 3). The Examiner concludes that “[vjiewed as a whole, these additional claim element(s) do not provide meaningful limitation(s) to transform the abstract idea into a patent eligible application of the abstract 3 Appeal 2016-002226 Application 12/084,608 idea such that the claim(s) amounts to significantly more than the abstract idea itself’ (Final Act. 4). The issue with respect to this rejection is: Does the evidence of record support the Examiner’s conclusion that claim 28 is directed to non- statutory subject matter? Findings of Fact 1. The Specification teaches: “Preferably, the user interface is provided through a conventional Internet browser such as Microsoft Explorer or Mozilla” (Spec. 9:7—9); that “the telecommunications network 2 includes the Internet and/or an Intranet, making server 3 accessible as a web server through the World Wide Web” (Spec. 8:12—14); and that “a conventional sequencer 5 [] provides the personal computer 11 with sequence data of DNA (Deoxyribonucleic Acid) fragments” (Spec. 8:1—3). 2. The Specification teaches “database 4 may be implemented on a computer shared with server 3 or on a separate computer” (Spec. 8:25—26) but provides no specific technologic modification of the database, server, or computer. 3. The Specification recites the language of claim 28, with “organism-type specific profile” information, and steps of correlating this information, selecting the highest correlation, retrieving and comparing related sequences, and weighting the comparison to obtain an “optimal organism type-specific reference sequence” (see Spec. 9:19 to 16:10), but the Specification provides no specific algorithms or specific technical implementations other than high level discussions of data manipulation. 4 Appeal 2016-002226 Application 12/084,608 Principles of Law [W]e set forth a framework for distinguishing patents that claim laws of nature, natural phenomena, and abstract ideas from those that claim patent-eligible applications of those concepts. First, we determine whether the claims at issue are directed to one of those patent-ineligible concepts. If so, we then ask, “[w]hat else is there in the claims before us?” To answer that question, we consider the elements of each claim both individually and “as an ordered combination” to determine whether the additional elements “transform the nature of the claim” into a patent-eligible application. We have described step two of this analysis as a search for an “inventive concept” - -i.e., an element or combination of elements that is “sufficient to ensure that the patent in practice amounts to significantly more than a patent upon the [ineligible concept] itself.” Alice Corp. Pty. Ltd. v. CLS Bank Inti, 134 S. Ct. 2347, 2355 (2014). Analysis We agree with and adopt the Examiner’s findings of fact and reasoning regarding the conclusion that claim 28 is unpatentable as being directed to non-statutory subject matter (Final Act. 3^4; Ans. 3—9; FF 1—3). We address Appellant’s arguments below. Appellant “submit[s] that each of claims 2, 4—9, 28, and 29 is not directed to an abstract idea” (Appeal Br. 5). Rather, Appellant contends, [cjlaim 28 provides far more detail than a mere “typ[e] of concept” such as listed in the Interim Guidelines. See Interim Guidelines, 79 Fed. Reg. 74622 (Dec. 16, 2014). Further, the level of recited detail substantially reduces the risk that all of the subject matter based on abstract ideas underpinning claim 28 (and claim 29) will be tied up (App. Br. 9). We do not find this argument persuasive because the focus of claim 28 is on an abstract idea: collecting information analyzing it to identify or 5 Appeal 2016-002226 Application 12/084,608 classify organisms using weighting factors associated with informative sequence regions, and determining optimal reference sequences for use in organism classification based on this analysis. Appellant contends, however, that claim 28 recites “features which, when taken together, provide meaningful advantages over previous techniques” (Appeal Br. 6). Appellant points to claim 28’s recitation of obtaining target sequences at a server, providing a database that comprises profiles associated with sequences, and performing correlation and selection steps to ultimately identify an optimal informative sequence for use in an identification or classification process (App. Br. 7—8; see Claim 28; FF 3). According to Appellant, these elements “are more than mathematical concepts such as mathematical algorithms, mathematical relationships, mathematical formulas, and calculations” (Reply Br. 5). We do not find Appellant’s argument persuasive. As our reviewing court recently noted, “[precedent has recognized that specific technologic modifications to solve a problem or improve the functioning of a known system generally produce patent-eligible subject matter.” Trading Techs. Int’l, Inc. v. CQG, Inc., 2017 WL 192716 *3 (Fed. Cir. 2017) (non- precedential). We do not find that to be the case here. Appellant does not assert that claim 28 requires an arguably inventive device or technique for displaying information or new techniques for analyzing information. Thus, this case is unlike DDR Holdings, LLC v. Hotels.com, L.P., 773 F.3d 1245, 1257 (Fed. Cir. 2014), finding an inventive concept in modification of conventional mechanics behind website display to produce dual-source integrated hybrid display. 6 Appeal 2016-002226 Application 12/084,608 Appellant also does not argue that the invention is a software-based invention that improves the performance of the computer system itself. Thus, this case is also unlike Bascom Global Internet Servs., Inc. v. AT&T Mobility LLC, 827 F.3d 1341, 1350 (Fed. Cir. 2016), which found an inventive concept in the ordered combination of limitations providing for “the installation of a filtering tool at a specific location, remote from the end-users, with customizable filtering features specific to each end user.” We note that “[c]laims directed to the ‘process of gathering and analyzing information of a specified content, then displaying the results, ’ without ‘any particular assertedly inventive technology for performing those functions,’ were held ineligible in Electric Power Grp., LLC v. Alstom S.A., 830 F.3d 1350, 1354 (Fed. Cir. 2016).” Trading Techs. *4. We find claim 28 to be analogous to that held patent ineligible in Electric Power. There can be no reasonable dispute that the steps of obtaining a target sequence, providing a database comprising those sequences, and correlating that data to obtain sequence alignments represent conventional steps (FF 1— 3; cf. Spec 1:16 to 2:6 which describes as “conventional” the use of target sequences and a reference database to build sequence alignments and obtain correlation information regarding those sequences). Thus, the only step that substantively differs from the admitted conventional steps is the selection of weighting factors used to obtain “an optimal organism type-specific reference sequence.” However, Appellant does not explain how the mere act of selecting undisclosed and unidentified “weighting factors” or a generically disclosed “optimal organism type-specific reference sequence” is transformative. “Merely requiring the selection and manipulation of 7 Appeal 2016-002226 Application 12/084,608 information—to provide a ‘humanly comprehensible’ amount of information useful for users,. . . —by itself does not transform the otherwise-abstract processes of information collection and analysis.” Electric Power, 830 F.3d at 1355. Appellant’s claimed organism classification process does not provide any technological advance to the process of analyzing the data or displaying it. For example, there are not any limited and new mathematical rules applied to the data. Nor is there any improvement in the way the system components operate to analyze, correlate, compare, or weight the information, or determine optimal organism type-specific reference sequences based on these data manipulations. Thus, we agree with the Examiner that the claim limitations, analyzed alone and in combination, fail to add “something more” to “transform” the claimed abstract idea of weighting informative sequence regions to obtain optimal reference sequences for use in organism classification into “a patent-eligible application.” See Alice Corp. v. CLS Bank International, 134 S. Ct. 2347, 2354, 2357 (2014). Appellant contends that the “claimed invention is a technical solution to a technical problem” (App. Br. 10) and that the “claims are directed to using computation to organism type-specific profiles to improve classifying organism types from target gene sequences” (App. Br. 11). Appellant also contends that Smartgene Inc. v. Advanced Biological Laboratories, SA, 555 Fed. Appx. 950 (Fed. Cir. 2014) (non-precedential), cited by the Examiner is not controlling because “the patent-ineligible claims at issue in SmartGene are not analogous to Appellants’ patent-eligible claims” (Reply Br. 12). 8 Appeal 2016-002226 Application 12/084,608 Appellant contends that “claims 28 and 29 recite significantly more ‘than call on a “computing device” with basic functionality’, and thus are not analogous to the claims at issue in SmartGene” (Reply Br. 12). We do not find these arguments persuasive. Our reviewing court found the claims at issue in Smartgene patent ineligible because they did “no more than call on a ‘computing device,’ with basic functionality for comparing stored and input data and rules, to do what doctors do routinely.” SmartGene, 555 Fed. Appx. at 954. We agree with the Examiner that, in the instant case, the “‘organism type-specific profiles’, as claimed, is/are nothing more than sequence data that is being used in an algorithm process that calls on a server (i.e. computer) for providing and processing this DATA using mathematical comparisons and rule-based processes” (Ans. 8). In other words, the claimed steps do not rely on an inventive device or technique for displaying information or new techniques for analyzing information, but rather constitute “a generic recitation of steps for mathematically manipulating data to obtained ‘optimal’ sequence data” (Ans. 7). The instant facts are also similar to those in SmartGene because the claims at issue in SmartGene relied upon “expert rules” for “‘evaluating and selecting’ from a stored ‘plurality of different therapeutic treatment regimens.’” SmartGene, 555 Fed. Appx. at 951—952, claim 1). The “expert rules” in SmartGene are analogous to the “weighting factors” used to determine “an optimal organism type-specific reference sequence” in claim 28. In neither SmartGene nor the instant claims is there any evidence of record that specific rules or factors were required. The claims thus 9 Appeal 2016-002226 Application 12/084,608 encompass the use of any rule or factor known or desired for use in the computing device. Accordingly we affirm the Examiner’s rejection of claim 28. Claims 2, 4—9, and 29 have not been argued separately and, therefore, fall with claim 28. 37 C.F.R. § 41.37(c)(l)(iv). SUMMARY We affirm the rejection of claims 2, 4—9, 28 and 29 under 35 U.S.C. § 101 as being directed to non-statutory subject matter. No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). AFFIRMED 10 Copy with citationCopy as parenthetical citation