Ex Parte Deutsch et alDownload PDFPatent Trial and Appeal BoardApr 20, 201713852288 (P.T.A.B. Apr. 20, 2017) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 13/852,288 03/28/2013 Thomas W. Deutsch END920120233US2 2570 7590 Brown & Michaels (END) c/o Brown & Michaels, PC 118 North Tioga Street Suite 400 Ithaca, NY 14850 EXAMINER NEGIN, RUSSELL SCOTT ART UNIT PAPER NUMBER 1631 NOTIFICATION DATE DELIVERY MODE 04/24/2017 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): docket@bpmlegal.com lwood@bpmlegal.com twood@bpmlegal.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte THOMAS W. DEUTSCH, ROBERT R. FRIEDLANDER, JAMES R. KRAEMER, and JOSKO SILOBRCIC1 Appeal 2016-006123 Application 13/852,288 Technology Center 1600 Before ERIC B. GRIMES, MELANIE L. McCOLLUM, and JOHN E. SCHNEIDER, Administrative Patent Judges. SCHNEIDER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal under 35U.S.C. § 134 involving claims to methods for analyzing epigenetic data, which have been rejected as being directed to non-statutory subject matter. We have jurisdiction under 35 U.S.C. § 6(b). We affirm. STATEMENT OF THE CASE The Specification teaches that Epigenetics includes the study of heritable changes in gene expression that are not due to changes in DNA sequence, 1 Appellants identify the Real Party in Interest as International Business Machines Corporation. Appeal Br. 1. Appeal 2016-006123 Application 13/852,288 in other words, all modifications to genes other than changes to the DNA sequence itself. Examples of modifications are DNA methylation, histone modification, chromatic accessibility, acetylation, phosphorylation, ubiquitination, ADP-ribosylation and others. The modifications alter the chromatin structure of the DNA and its accessibility, and therefore the regulation of gene expression patterns. The pattern of gene expression can also be modified by exogenous influences, such as environmental influences including nutrition. These modifications can persist throughout an organism’s lifetime and be passed onto to future generations. Spec. 13. The present invention is directed to a method for reducing an amount of “epigenetic data representing epigenetic modifications of a genetic sequence of an organism using a file distributed system.” Spec. 1 8. Claims 1—18 are on appeal. Claim 1 is representative of the rejected claims and reads as follows: 1. A method for reducing an amount of epigenetic data representing epigenetic modifications of a genetic sequence of an organism using a file distributed system comprising a series of clusters coupled together, each cluster having at least one master node and a plurality of worker nodes, comprising: a computer comprising one of the master nodes of one of the clusters of the file distributed system breaking a reference epigenetic map and epigenetic data from at least one point in time into blocks of data of a fixed size; the computer distributing the blocks of data to the plurality of worker nodes within the clusters and replicating the blocks of data within each of the worker nodes; the computer tasking the plurality of worker nodes to perform a map job comprising mapping the reference epigenetic map relative to the epigenetic data from at least a point in time by: 2 Appeal 2016-006123 Application 13/852,288 comparing a subset of the epigenetic data representing epigenetic modifications of a genetic sequence of an organism to the mapped part of a genetic sequence of the reference epigenetic map, to find differences where epigenetic modifications of the genetic sequence of the organism are different from the mapped part of the genetic sequence of the reference epigenetic map; storing intermediate surprisal data in a key and value format in a repository of the cluster, the intermediate surprisal data comprising at least a starting location of the epigenetic modifications within the reference epigenetic map, and the modifications from the genetic sequence of the organism which are different from the reference epigenetic map, discarding modifications of the reference epigenetic map that are the same in the genetic sequence of the organism; and reporting the status of the task to map the reference epigenetic map to the epigenetic map at a specific point in time to the at least one master node of the cluster; when a worker node has reported a completion of the map job, the computer tasking the worker node with a reduce job based on a specific key, comprising: the worker node shuffling the intermediate surprisal data between the worker node and a plurality of worker nodes of other clusters, based on the specific key; and the worker node reducing the intermediate surprisal data to an output of epigenetic surprisal data and associated metadata. Claims 1—18 stand rejected under 35 U.S.C. § 101 as directed to non- statutory subject matter. 3 Appeal 2016-006123 Application 13/852,288 DISCUSSION Issue The issue is whether a preponderance of evidence supports the Examiner’s conclusion that claims 1—18 are directed to non-statutory subject matter. The Examiner finds that the rejected claims are directed to an abstract idea and are therefore directed to non-statutory subject matter. Final Act. 3^4. The Examiner finds that using a computer to distribute work between nodes is conventional and routine and does not represent something significantly more that the abstract idea. Id. Appellants contend that the claimed method is patentable as the method does not fall within one of the four listed categories of abstract ideas identified by the USPTO and the courts. Appeal Br. 11. Appellants argue that the use of a computer does not automatically trigger an eligibility analysis. Id. Appellants contend that the specific steps recited in the claims represent something significantly more than the abstract idea of analyzing the epigenetic data. Id. at 12. Appellants also argue that the claimed method does not preclude the use of other methods to reduce epigenetic data and that this indicates that the claims are not directed to non-statutory subject matter. Reply Br. 6. Analysis As stated in In re Oetiker, 977 F.2d 1443, 1445 (Fed. Cir. 1992): [T]he examiner bears the initial burden ... of presenting a prima facie case of unpatentability. . . . After evidence or argument is submitted by the applicant in response, patentability is determined on the totality of the 4 Appeal 2016-006123 Application 13/852,288 record, by a preponderance of evidence with due consideration to persuasiveness of argument. Appellants do not persuade us that a preponderance of the evidence fails to support the Examiner’s conclusion that the rejected claims recite subject matter ineligible for patenting under 35 U.S.C. § 101, which states that “[wjhoever invents or discovers any new and useful process, machine, manufacture, or composition of matter, or any new and useful improvement thereof, may obtain a patent therefor, subject to the conditions and requirements of this title.” The Supreme Court has “long held that this provision contains an important implicit exception: Laws of nature, natural phenomena, and abstract ideas are not patentable.” Alice Corp. Pty. Ltd. v. CLS Banklnt’l, 134 S. Ct. 2347, 2354 (2014). Our reviewing court has summarized the Supreme Court’s two-part test for distinguishing between claims to patent-ineligible exceptions, and claims to patent-eligible applications of those exceptions, as follows: Step one asks whether the claim is “directed to one of [the] patent-ineligible concepts.” [Alice, 134 S. Ct. at 2354], If the answer is no, the inquiry is over: the claim falls within the ambit of § 101. If the answer is yes, the inquiry moves to step two, which asks whether, considered both individually and as an ordered combination, “the additional elements ‘transform the nature of the claim’ into a patent-eligible application.” Id. (quoting Mayo [Collaborative Services v. Prometheus Labs, Inc., 132 S. Ct. 1289, 1297 (2012)]). Step two is described “as a search for an ‘inventive concept.’” Id. (quoting Mayo, 132 S.Ct. at 1294). At step two, more is required than “well- understood, routine, conventional activity already engaged in by the scientific community,” which fails to transform the claim 5 Appeal 2016-006123 Application 13/852,288 into “significantly more than a patent upon the” ineligible concept itself. Mayo, 132 S.Ct. at 1298, 1294. Rapid Litigation Mgmt. Ltd. v. CellzDirect, Inc., 827 F.3d 1042, 1047 (Fed. Cir. 2016) (paragraphing added). In the present case, claim 1 recites the steps of “breaking a reference epigenetic map and epigenetic data from at least one point in time into blocks of data of fixed size,” “distributing the blocks of data to the plurality of worker nodes within the clusters and replicating the blocks of data within each of the worker nodes,” “tasking the plurality of worker nodes to perform a map job comprising mapping the reference epigenetic map relative to the epigenetic data from at least a point in time,” and comparing subsets of epigenetic data. Appeal Br. 15 (Claims Appendix). We agree with the Examiner that the recited steps involve mathematical manipulations of computational data which falls within the category of mathematical relationships. “Without additional limitations, a process that employs mathematical algorithms to manipulate existing information to generate additional information is not patent eligible.” Digitech Image Techs, v. Electronics for Imaging, Inc., 758 F.3d 1344, 1351 (Fed. Cir. 2014). As to part two of the Supreme Court’s test, we agree with the Examiner that the claims do not recite any additional steps or limitations which transform the claim into something significantly more than the judicial exception. Ans. 3. We agree with the Examiner that each of the limitations recited by Appellants as representing something significantly more are themselves abstract ideas. Ans. 3. Appellants have offered 6 Appeal 2016-006123 Application 13/852,288 nothing persuasive to support their contention that the recited steps represent something significantly more than abstract ideas. Id. We, therefore, agree with the Examiner that, under the Supreme Court’s two-part test, claim 1 recites subject matter ineligible for patenting under § 101. Appellants’ arguments do not persuade us to the contrary. Appellants contend that the method recited in the claims does not fall within one of the specific categories of abstract ideas found to be ineligible subject matter. Appeal Br. 11. For the reasons stated above, we find this argument unpersuasive. Appellants also contend that the recited steps represent something significantly more that an abstract idea rendering the method eligible for patent protection. Appeal Br. 12. As discussed above, the recited steps themselves are abstract ideas and do not render the claimed method patentable. We are also not persuaded by Appellants’ argument that the claims do not preempt the idea of reduction of epigenetic data as the claims are directed to a specific method for reducing the data. Reply Br. 6. Our reviewing court has expressly rejected similar contentions regarding preemption, stating that a patentee’s “attempt to limit the breadth of the claims by showing alternative uses . . . outside of the scope of the claims does not change the conclusion that the claims are directed to patent ineligible subject matter.” Ariosa Diagnostics, Inc. v. Sequenom, Inc., 788 F.3d 1371, 1379 (Fed. Cir. 2015). The court explained that, “[wjhile preemption may signal patent ineligible subject matter, the absence of 7 Appeal 2016-006123 Application 13/852,288 complete preemption does not demonstrate patent eligibility. . . . Where a patent’s claims are deemed only to disclose patent ineligible subject matter under the Mayo framework . . . preemption concerns are fully addressed and made moot.” Id. In the present case, as discussed above, Appellants’ claim 1 is limited to patented ineligible subject matter under the Mayo framework. Thus, the fact that alternatives outside the claims are not preempted does not demonstrate patent eligibility. In sum, for the reasons discussed, Appellants do not persuade us that a preponderance of the evidence fails to support the Examiner’s conclusion that Appellants’ claims 1—18 are patent-ineligible under § 101. Accordingly, we affirm the Examiner’s rejection of claims 1—18. SUMMARY We affirm the rejection under 35 U.S.C. § 101. TIME PERIOD FOR RESPONSE No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). AFFIRMED 8 Copy with citationCopy as parenthetical citation