Upon the discovery of the existance of a bee disease or infestation of bee parasites within a colony of bees resident (whether temporarily or permanently, but not in transit) in Massachusetts, or upon a determination by the Chief Apiary Inspector or his agent that a substantial likelihood exists that such a colony of bees has been exposed to such diseases or parasites and as a consequence may be, or may become, diseased or infested with such disease or parasites; the owner of such bee colonies or his agent or representative or the caretaker of such colony shall cause all such colonies to be treated in such a manner as the Chief Apiary Inspector or his agent may direct.
330 CMR, § 8.07