S.C. Code Regs. § § 61-20.3
The Department shall investigate a known or suspected Case of a Reportable Condition within the state and within the designated time frame for the Condition in accordance with CDC or Department protocols. For purposes of report verification and epidemiological investigation, the Department may conduct appropriate follow-up of reports of positive tests, Conditions, clusters of diseases, or Events. Such verification and investigation may include, but may not be limited to: confirmation of test results or reports; collection and confirmation of other information required to be reported; review of healthcare records; and interviews of patients, Contacts, physicians and other appropriate healthcare staff. If the person infected with the Condition is incompetent, incapacitated or deceased, the Department may interview the guardian, next of kin, and/or spouse.
S.C. Code Regs. § 61-20.3